Rosuvastatin, atorvastatin: similar effectiveness in LODESTAR, some different signals

Rosuvastatin, atorvastatin: similar effectiveness in LODESTAR, some different signals

This secondary analysis showed more diabetes and cataracts, but more effective treatment of LDL cholesterol with rosuvastatin. Among people with coronary artery disease, rosuvastatin and atorvastatin are both effective in reducing all-cause death, MI, stroke or any coronary revascularization over 3 years, analysis shows secondary study of the LODESTAR trial. Notably, although the former was …

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Review: Similar safety profiles of the reference pegfilgrastim biosimilar in clinical studies

Review: Similar safety profiles of the reference pegfilgrastim biosimilar in clinical studies

Filgrastim and pegfilgrastim are recombinant human granulocyte colony-stimulating factor (G-CSF) analogs used to prevent cancer patients from developing febrile neutropenia following chemotherapy. Pegfilgrastim biosimilars currently approved or filed for approval in the United States have demonstrated a high degree of similarity and comparability to the reference product, with no unexpected safety findings, concluded the authors …

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